Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 20, 2010 | Bishop Brossart | home | L | 19–34 | 0-1 | ||
| Fri, Aug 27, 2010 | Burch, WV | home | W | 52–6 | 1-1 | ||
| Fri, Sep 10, 2010 | Jackson County | away | W | 32–6 | 2-1 | ||
| Fri, Sep 17, 2010 | Magoffin County | home | L | 12–48 | 2-2 | ||
| Fri, Sep 24, 2010 | Phelps | home | W | 59–14 | 3-2 | ||
| Fri, Oct 1, 2010 | South Floyd | away | W | 66–14 | 4-2 | ||
| Fri, Oct 8, 2010 | Paintsville | away | W | 19–6 | 5-2 | ||
| Fri, Oct 15, 2010 | Pikeville | away | L | 20–47 | 5-3 | ||
| Fri, Oct 22, 2010 | Allen Central | home | W | 28–26 | 6-3 | overtime | |
| Fri, Oct 29, 2010 | Jenkins | home | W | 56–12 | 7-3 | ||
| Fri, Nov 5, 2010 | Pineville | home | L | 20–22 | 7-4 | 2010 Class 1A KHSAA Commonwealth Gridiron Bowl |