Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Sat, Aug 21, 2021 | Clay County | away | W | 30–22 | 1-0 | ||
| Fri, Aug 27, 2021 | Bell County | away | L | 14–22 | 1-1 | ||
| Fri, Sep 3, 2021 | South Laurel | home | W | 1–0 | 2-1 | COVID Cancelation - RPI per policy | |
| Fri, Sep 10, 2021 | Harlan County | away | W | 42–26 | 3-1 | ||
| Fri, Sep 17, 2021 | Paintsville | home | L | 14–34 | 3-2 | Appalachian Wireless Bowl | |
| Fri, Sep 24, 2021 | Open | 0–0 | |||||
| Fri, Oct 1, 2021 | Bourbon County | home | L | 20–35 | 3-3 | ||
| Fri, Oct 8, 2021 | Corbin | home | L | 0–56 | 3-4 | ||
| Fri, Oct 15, 2021 | Wayne County | away | W | 21–10 | 4-4 | ||
| Fri, Oct 22, 2021 | Lincoln County | home | L | 26–36 | 4-5 | ||
| Fri, Oct 29, 2021 | Breathitt County | home | W | 41–35 | 5-5 | (overtime) | |
| Fri, Nov 5, 2021 | Lincoln County | away | L | 22–49 | 5-6 | 2021 Class 4A 2021 UK Orthopaedics State Football Finals |