Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 19, 2016 | Seneca | away | W | 33–0 | 1-0 | ||
| Fri, Aug 26, 2016 | DuPont Manual | away | L | 0–14 | 1-1 | ||
| Fri, Sep 2, 2016 | Moore | home | W | 55–10 | 2-1 | ||
| Fri, Sep 9, 2016 | Butler | home | W | 27–7 | 3-1 | ||
| Fri, Sep 16, 2016 | DeSales | away | L | 14–27 | 3-2 | ||
| Fri, Sep 23, 2016 | Fairdale | away | W | 47–0 | 4-2 | ||
| Thu, Sep 29, 2016 | Southern | home | W | 41–34 | 5-2 | ||
| Fri, Oct 7, 2016 | Doss | away | W | 41–20 | 6-2 | ||
| Sat, Oct 15, 2016 | Iroquois | home | W | 42–12 | 7-2 | ||
| Fri, Oct 21, 2016 | Atherton | away | W | 47–12 | 8-2 | ||
| Fri, Nov 4, 2016 | Grant County | home | W | 51–7 | 9-2 | 2016 Class 5A Russell Athletic/KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 11, 2016 | Dixie Heights | home | W | 39–6 | 10-2 | 2016 Class 5A Russell Athletic/KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 18, 2016 | Covington Catholic | home | W | 35–28 | 11-2 | 2016 Class 5A Russell Athletic/KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 25, 2016 | Bowling Green | home | L | 7–34 | 11-3 | 2016 Class 5A Russell Athletic/KHSAA Commonwealth Gridiron Bowl |