Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 27, 2010 | Casey County | home | W | 22–21 | 1-0 | ||
| Fri, Sep 3, 2010 | Knott County Central | home | W | 63–8 | 2-0 | ||
| Fri, Sep 10, 2010 | Breathitt County | home | W | 27–7 | 3-0 | ||
| Fri, Sep 17, 2010 | Logan, WV | home | W | 28–20 | 4-0 | ||
| Fri, Sep 24, 2010 | Letcher County Central | home | W | 50–23 | 5-0 | ||
| Fri, Oct 1, 2010 | North Laurel | home | W | 41–6 | 6-0 | ||
| Fri, Oct 8, 2010 | Clay County | away | L | 27–36 | 6-1 | ||
| Fri, Oct 15, 2010 | Harlan County | home | L | 7–50 | 6-2 | ||
| Fri, Oct 22, 2010 | Whitley County | away | L | 22–37 | 6-3 | ||
| Fri, Oct 29, 2010 | Leslie County | away | W | 49–28 | 7-3 | ||
| Fri, Nov 5, 2010 | Pulaski County | away | L | 6–37 | 7-4 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl |